L89F (p.Leu89Phe) variant of SLC40A1 (Ferroportin)
L89F (p.Leu89Phe) in SLC40A1 (Ferroportin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
L89F (p.Leu89Phe) variant details
- p.Leu89Phe
- TOPMed rs1387864275
- Missense
- Variant Prioritization Score for Impact Estimate 0.691
- REVEL 0.63
- CADD 24.40
- PolyPhen-2 0.93
- SIFT 0.17
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available