L60W (p.Leu60Trp) variant of SLC40A1 (Ferroportin)
L60W (p.Leu60Trp) in SLC40A1 (Ferroportin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
L60W (p.Leu60Trp) variant details
- p.Leu60Trp
- TOPMed rs1356919926
- gnomAD rs1356919926
- Missense
- Variant Prioritization Score for Impact Estimate 0.797
- REVEL 0.89
- CADD 29.20
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available