L27F (p.Leu27Phe) variant of SLC40A1 (Ferroportin)
L27F (p.Leu27Phe) in SLC40A1 (Ferroportin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
L27F (p.Leu27Phe) variant details
- p.Leu27Phe
- ExAC rs780093738
- TOPMed rs780093738
- gnomAD rs780093738
- Missense
- Variant Prioritization Score for Impact Estimate 0.597
- REVEL 0.48
- CADD 24.50
- PolyPhen-2 0.36
- SIFT 0.21
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available