I159V (p.Ile159Val) variant of SLC40A1 (Ferroportin)
I159V (p.Ile159Val) in SLC40A1 (Ferroportin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
I159V (p.Ile159Val) variant details
- p.Ile159Val
- ESP rs375694920
- ExAC rs375694920
- TOPMed rs375694920
- gnomAD rs375694920
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.33
- CADD 22.10
- PolyPhen-2 0.20
- SIFT 0.41
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available