F114S (p.Phe114Ser) variant of SLC40A1 (Ferroportin)
F114S (p.Phe114Ser) in SLC40A1 (Ferroportin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
F114S (p.Phe114Ser) variant details
- p.Phe114Ser
- TOPMed rs2031175912
- Missense
- Variant Prioritization Score for Impact Estimate 0.82
- REVEL 0.93
- CADD 29.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available