A140T (p.Ala140Thr) variant of SLC40A1 (Ferroportin)
A140T (p.Ala140Thr) in SLC40A1 (Ferroportin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
A140T (p.Ala140Thr) variant details
- p.Ala140Thr
- TOPMed rs2031136661
- Missense
- Variant Prioritization Score for Impact Estimate 0.802
- REVEL 0.83
- CADD 24.40
- PolyPhen-2 0.68
- SIFT 0.05
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available