L86F (p.Leu86Phe) variant of SLC35A2 (UDP-galactose translocator)
L86F (p.Leu86Phe) in SLC35A2 (UDP-galactose translocator) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
L86F (p.Leu86Phe) variant details
- p.Leu86Phe
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.10
- CADD 24.30
- PolyPhen-2 0.07
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 0.00011)
- Structural context available