Y69S (p.Tyr69Ser) variant of SLC30A8 (Q8IWU4)
Y69S (p.Tyr69Ser) in SLC30A8 (Q8IWU4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
Y69S (p.Tyr69Ser) variant details
- p.Tyr69Ser
- 1000Genomes rs547844916
- ExAC rs547844916
- TOPMed rs547844916
- gnomAD rs547844916
- Missense
- Variant Prioritization Score for Impact Estimate 0.105
- REVEL 0.08
- MetaLR 0.11
- MetaSVM -1.02
- CADD 1.62
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the 1KG:PJL population (allele frequency 0.0052)
- Structural context available