T60K (p.Thr60Lys) variant of SLC30A8 (Q8IWU4)
T60K (p.Thr60Lys) in SLC30A8 (Q8IWU4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
T60K (p.Thr60Lys) variant details
- p.Thr60Lys
- ExAC rs775528421
- gnomAD rs775528421
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.08
- MetaLR 0.12
- MetaSVM -1.03
- CADD 1.84
- PolyPhen-2 0.11
- SIFT 0.69
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available