P59S (p.Pro59Ser) variant of SLC30A8 (Q8IWU4)
P59S (p.Pro59Ser) in SLC30A8 (Q8IWU4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P59S (p.Pro59Ser) variant details
- p.Pro59Ser
- ExAC rs769900402
- gnomAD rs769900402
- Missense
- Variant Prioritization Score for Impact Estimate 0.163
- REVEL 0.07
- MetaLR 0.10
- MetaSVM -1.04
- CADD 8.55
- PolyPhen-2 0.00
- SIFT 0.15
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available