L27P (p.Leu27Pro) variant of SLC30A8 (Q8IWU4)
L27P (p.Leu27Pro) in SLC30A8 (Q8IWU4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
L27P (p.Leu27Pro) variant details
- p.Leu27Pro
- ExAC rs765261676
- TOPMed rs765261676
- gnomAD rs765261676
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.31
- CADD 21.20
- PolyPhen-2 0.00
- SIFT 0.16
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available