L27F (p.Leu27Phe) variant of SLC30A8 (Q8IWU4)
L27F (p.Leu27Phe) in SLC30A8 (Q8IWU4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L27F (p.Leu27Phe) variant details
- p.Leu27Phe
- ExAC rs759603427
- gnomAD rs759603427
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.07
- CADD 17.70
- SIFT 0.22
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available