G68R (p.Gly68Arg) variant of SLC2A4 (P14672)
G68R (p.Gly68Arg) in SLC2A4 (P14672) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G68R (p.Gly68Arg) variant details
- p.Gly68Arg
- rs1429679424
- NCI-TCGA Cosmic COSV9914
- cosmic curated COSV99142
- TOPMed rs1429679424
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.15
- CADD 22.00
- PolyPhen-2 0.00
- SIFT 0.54
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available