I10T (p.Ile10Thr) variant of SLC25A14 (O95258)
I10T (p.Ile10Thr) in SLC25A14 (O95258) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
I10T (p.Ile10Thr) variant details
- p.Ile10Thr
- gnomAD X-130340307-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.426
- REVEL 0.40
- ESM-1b 0.00
- AlphaMissense 0.31
- MetaLR 0.45
- MetaSVM -0.54
- CADD 25.60
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available
- Literature evidence available