A77T (p.Ala77Thr) variant of SLC25A14 (O95258)
A77T (p.Ala77Thr) in SLC25A14 (O95258) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
A77T (p.Ala77Thr) variant details
- p.Ala77Thr
- 1000Genomes rs748623528
- ExAC rs748623528
- TOPMed rs748623528
- gnomAD rs748623528
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.28
- ESM-1b 0.00
- AlphaMissense 0.08
- MetaLR 0.40
- MetaSVM -0.46
- CADD 22.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available