V121M (p.Val121Met) variant of SLC22A6 (Q4U2R8)
V121M (p.Val121Met) in SLC22A6 (Q4U2R8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
V121M (p.Val121Met) variant details
- p.Val121Met
- cosmic curated COSV64560
- 1000Genomes rs1389751480
- gnomAD rs1389751480
- Missense
- Variant Prioritization Score for Impact Estimate 0.646
- REVEL 0.58
- MetaLR 0.81
- MetaSVM 0.89
- CADD 25.20
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available