T115S (p.Thr115Ser) variant of SLC22A6 (Q4U2R8)
T115S (p.Thr115Ser) in SLC22A6 (Q4U2R8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T115S (p.Thr115Ser) variant details
- p.Thr115Ser
- TOPMed rs886137600
- gnomAD rs886137600
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.17
- MetaLR 0.29
- MetaSVM -0.82
- CADD 15.90
- PolyPhen-2 0.17
- SIFT 0.68
- Population evidence available
- Structural context available