L6F (p.Leu6Phe) variant of SLC22A6 (Q4U2R8)
L6F (p.Leu6Phe) in SLC22A6 (Q4U2R8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
L6F (p.Leu6Phe) variant details
- p.Leu6Phe
- TOPMed rs2086300277
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.35
- MetaLR 0.39
- MetaSVM -0.09
- CADD 23.90
- PolyPhen-2 0.70
- SIFT 0.09
- Population evidence available
- Structural context available