I110M (p.Ile110Met) variant of SLC22A6 (Q4U2R8)
I110M (p.Ile110Met) in SLC22A6 (Q4U2R8) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
I110M (p.Ile110Met) variant details
- p.Ile110Met
- NCI-TCGA TCGA novel
- Ensembl rs2086292487
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.06
- MetaLR 0.17
- MetaSVM -0.79
- CADD 23.30
- PolyPhen-2 0.25
- SIFT 0.09
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available