I110L (p.Ile110Leu) variant of SLC22A6 (Q4U2R8)
I110L (p.Ile110Leu) in SLC22A6 (Q4U2R8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
I110L (p.Ile110Leu) variant details
- p.Ile110Leu
- ExAC rs766737752
- gnomAD rs766737752
- Missense
- Variant Prioritization Score for Impact Estimate 0.117
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -1.03
- CADD 15.70
- PolyPhen-2 0.00
- SIFT 0.14
- Population evidence available
- Structural context available