F81L (p.Phe81Leu) variant of SLC22A6 (Q4U2R8)
F81L (p.Phe81Leu) in SLC22A6 (Q4U2R8) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
F81L (p.Phe81Leu) variant details
- p.Phe81Leu
- TOPMed rs1212228005
- gnomAD rs1212228005
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.28
- MetaLR 0.21
- MetaSVM -0.60
- CADD 23.40
- PolyPhen-2 0.11
- SIFT 0.03
- Population evidence available
- Structural context available