T45I (p.Thr45Ile) variant of SLC22A5 (O76082)
T45I (p.Thr45Ile) in SLC22A5 (O76082) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T45I (p.Thr45Ile) variant details
- p.Thr45Ile
- Ensembl rs1751834531
- Missense
- Variant Prioritization Score for Impact Estimate 0.363
- REVEL 0.21
- AlphaMissense 0.18
- MetaLR 0.35
- MetaSVM -0.75
- CADD 14.40
- PolyPhen-2 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available