L37L (p.Leu37Leu) variant of SLC22A5 (O76082)
L37L (p.Leu37Leu) in SLC22A5 (O76082) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
L37L (p.Leu37Leu) variant details
- p.Leu37Leu
- rs796052037
- gnomAD 5-132370081-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.234
- AlphaMissense 0.20
- MetaLR 0.48
- MetaSVM -0.74
- CADD 7.86
- PolyPhen-2 0.00
- SIFT 0.93
- Most common in the Finnish in Finland (FIN) population (allele frequency 7.6e-05)
- Structural context available
- Literature evidence available