V75M (p.Val75Met) variant of SLC22A2 (O15244)
V75M (p.Val75Met) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
V75M (p.Val75Met) variant details
- p.Val75Met
- cosmic curated COSV10467
- TOPMed rs1783317137
- gnomAD rs1783317137
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.33
- CADD 22.40
- PolyPhen-2 0.52
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available