T74R (p.Thr74Arg) variant of SLC22A2 (O15244)
T74R (p.Thr74Arg) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data and structural context.
T74R (p.Thr74Arg) variant details
- p.Thr74Arg
- ExAC rs769783921
- gnomAD rs769783921
- Missense
- Variant Prioritization Score for Impact Estimate 0.723
- REVEL 0.69
- CADD 25.80
- PolyPhen-2 1.00
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available