T74A (p.Thr74Ala) variant of SLC22A2 (O15244)
T74A (p.Thr74Ala) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
T74A (p.Thr74Ala) variant details
- p.Thr74Ala
- TOPMed rs893408492
- Missense
- Variant Prioritization Score for Impact Estimate 0.518
- REVEL 0.43
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available