S109N (p.Ser109Asn) variant of SLC22A2 (O15244)
S109N (p.Ser109Asn) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
S109N (p.Ser109Asn) variant details
- p.Ser109Asn
- TOPMed rs941242974
- gnomAD rs941242974
- Missense
- Variant Prioritization Score for Impact Estimate 0.144
- REVEL 0.04
- CADD 15.70
- PolyPhen-2 0.02
- SIFT 0.34
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available