R52W (p.Arg52Trp) variant of SLC22A2 (O15244)
R52W (p.Arg52Trp) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
R52W (p.Arg52Trp) variant details
- p.Arg52Trp
- TOPMed rs1783319808
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.11
- CADD 12.90
- PolyPhen-2 0.00
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available