R116H (p.Arg116His) variant of SLC22A2 (O15244)
R116H (p.Arg116His) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
R116H (p.Arg116His) variant details
- p.Arg116His
- ExAC rs766277243
- gnomAD rs766277243
- Missense
- Variant Prioritization Score for Impact Estimate 0.152
- REVEL 0.17
- CADD 9.27
- PolyPhen-2 0.00
- SIFT 0.37
- Most common in the Latino/Admixed American population (allele frequency 2.3e-05)
- Structural context available