P35R (p.Pro35Arg) variant of SLC22A2 (O15244)
P35R (p.Pro35Arg) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
P35R (p.Pro35Arg) variant details
- p.Pro35Arg
- ExAC rs780658045
- TOPMed rs780658045
- gnomAD rs780658045
- Missense
- Variant Prioritization Score for Impact Estimate 0.606
- REVEL 0.50
- CADD 23.10
- PolyPhen-2 0.94
- SIFT 0.08
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available