L59V (p.Leu59Val) variant of SLC22A2 (O15244)
L59V (p.Leu59Val) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
L59V (p.Leu59Val) variant details
- p.Leu59Val
- gnomAD rs1783319053
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.39
- CADD 22.80
- PolyPhen-2 0.64
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available