L25F (p.Leu25Phe) variant of SLC22A2 (O15244)
L25F (p.Leu25Phe) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L25F (p.Leu25Phe) variant details
- p.Leu25Phe
- ExAC rs773286352
- gnomAD rs773286352
- Missense
- Variant Prioritization Score for Impact Estimate 0.21
- REVEL 0.14
- CADD 14.50
- PolyPhen-2 0.01
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available