G79R (p.Gly79Arg) variant of SLC22A2 (O15244)
G79R (p.Gly79Arg) in SLC22A2 (O15244) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
G79R (p.Gly79Arg) variant details
- p.Gly79Arg
- NCI-TCGA Cosmic COSV6526
- cosmic curated COSV65267
- gnomAD rs1410111608
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.27
- CADD 22.70
- PolyPhen-2 0.92
- SIFT 0.07
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available