G77V (p.Gly77Val) variant of SLC22A2 (O15244)
G77V (p.Gly77Val) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
G77V (p.Gly77Val) variant details
- p.Gly77Val
- cosmic curated COSV10087
- ESP rs375277138
- ExAC rs375277138
- TOPMed rs375277138
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.23
- CADD 20.40
- PolyPhen-2 0.46
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available