F45S (p.Phe45Ser) variant of SLC22A2 (O15244)
F45S (p.Phe45Ser) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
F45S (p.Phe45Ser) variant details
- p.Phe45Ser
- TOPMed rs1783320756
- gnomAD rs1783320756
- Missense
- Variant Prioritization Score for Impact Estimate 0.595
- REVEL 0.63
- CADD 26.20
- PolyPhen-2 1.00
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available