D111Y (p.Asp111Tyr) variant of SLC22A2 (O15244)
D111Y (p.Asp111Tyr) in SLC22A2 (O15244) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
D111Y (p.Asp111Tyr) variant details
- p.Asp111Tyr
- ESP rs370743058
- ExAC rs370743058
- TOPMed rs370743058
- gnomAD rs370743058
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.16
- CADD 21.10
- PolyPhen-2 0.10
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available