W64R (p.Trp64Arg) variant of SLC22A1 (O15245)
W64R (p.Trp64Arg) in SLC22A1 (O15245) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data, published literature, and structural context.
W64R (p.Trp64Arg) variant details
- p.Trp64Arg
- gnomAD 6-160122125-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.647
- REVEL 0.76
- CADD 25.70
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available
- Literature evidence available