W16L (p.Trp16Leu) variant of SLC22A1 (O15245)
W16L (p.Trp16Leu) in SLC22A1 (O15245) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
W16L (p.Trp16Leu) variant details
- p.Trp16Leu
- TOPMed rs1374644494
- gnomAD rs1374644494
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.14
- CADD 17.40
- PolyPhen-2 0.00
- SIFT 0.70
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available