W16C (p.Trp16Cys) variant of SLC22A1 (O15245)
W16C (p.Trp16Cys) in SLC22A1 (O15245) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
W16C (p.Trp16Cys) variant details
- p.Trp16Cys
- gnomAD rs1226022756
- Missense
- Variant Prioritization Score for Impact Estimate 0.569
- REVEL 0.48
- CADD 22.60
- PolyPhen-2 0.59
- SIFT 0.18
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available