V37L (p.Val37Leu) variant of SLC22A1 (O15245)
V37L (p.Val37Leu) in SLC22A1 (O15245) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
V37L (p.Val37Leu) variant details
- p.Val37Leu
- ExAC rs761516344
- gnomAD rs761516344
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.14
- CADD 16.90
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available