T45I (p.Thr45Ile) variant of SLC22A1 (O15245)
T45I (p.Thr45Ile) in SLC22A1 (O15245) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
T45I (p.Thr45Ile) variant details
- p.Thr45Ile
- cosmic curated COSV61452
- 1000Genomes rs190270215
- ExAC rs190270215
- TOPMed rs190270215
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.11
- CADD 4.50
- PolyPhen-2 0.07
- SIFT 0.18
- Most common in the 1KG:JPT population (allele frequency 0.0049)
- Structural context available