I35T (p.Ile35Thr) variant of SLC22A1 (O15245)
I35T (p.Ile35Thr) in SLC22A1 (O15245) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
I35T (p.Ile35Thr) variant details
- p.Ile35Thr
- ExAC rs765568729
- gnomAD rs765568729
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.33
- CADD 22.00
- PolyPhen-2 0.15
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available