I35G (p.Ile35Gly) variant of SLC22A1 (O15245)
I35G (p.Ile35Gly) in SLC22A1 (O15245) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
I35G (p.Ile35Gly) variant details
- p.Ile35Gly
- rs776450090
- gnomAD 6-160122036-CCATC
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.567
- CADD 24.20
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available
- Literature evidence available