G63S (p.Gly63Ser) variant of SLC22A1 (O15245)
G63S (p.Gly63Ser) in SLC22A1 (O15245) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G63S (p.Gly63Ser) variant details
- p.Gly63Ser
- ExAC rs752617602
- TOPMed rs752617602
- gnomAD rs752617602
- Missense
- Variant Prioritization Score for Impact Estimate 0.591
- REVEL 0.60
- CADD 25.90
- PolyPhen-2 0.76
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 4.5e-05)
- Structural context available