C36Y (p.Cys36Tyr) variant of SLC22A1 (O15245)
C36Y (p.Cys36Tyr) in SLC22A1 (O15245) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
C36Y (p.Cys36Tyr) variant details
- p.Cys36Tyr
- ExAC rs753028126
- TOPMed rs753028126
- gnomAD rs753028126
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.16
- CADD 5.81
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available