T74I (p.Thr74Ile) variant of SLC12A3 (P55017)
T74I (p.Thr74Ile) in SLC12A3 (P55017) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
T74I (p.Thr74Ile) variant details
- p.Thr74Ile
- TOPMed rs1196986842
- gnomAD rs1196986842
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- CADD 12.30
- PolyPhen-2 0.04
- SIFT 0.44
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available