K45K (p.Lys45Lys) variant of SIX1 (Homeobox protein SIX1)
K45K (p.Lys45Lys) in SIX1 (Homeobox protein SIX1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
K45K (p.Lys45Lys) variant details
- p.Lys45Lys
- gnomAD 14-60649055-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.388
- CADD 13.90
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- SIX1 Homeobox domain domainome 1.0: score -0.736
- Literature evidence available