G24S (p.Gly24Ser) variant of SIX1 (Homeobox protein SIX1)
G24S (p.Gly24Ser) in SIX1 (Homeobox protein SIX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, experimental measurements, and structural context.
G24S (p.Gly24Ser) variant details
- p.Gly24Ser
- Ensembl rs754869969
- Missense
- Variant Prioritization Score for Impact Estimate 0.722
- CADD 21.70
- PolyPhen-2 0.00
- SIFT 0.72
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available
- SIX1 Homeobox domain domainome 1.0: score 0.0051