F63L (p.Phe63Leu) variant of SIX1 (Homeobox protein SIX1)
F63L (p.Phe63Leu) in SIX1 (Homeobox protein SIX1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
F63L (p.Phe63Leu) variant details
- p.Phe63Leu
- gnomAD rs1335186361
- Missense
- Variant Prioritization Score for Impact Estimate 0.525
- CADD 24.80
- PolyPhen-2 0.11
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available