D41D (p.Asp41Asp) variant of SIX1 (Homeobox protein SIX1)
D41D (p.Asp41Asp) in SIX1 (Homeobox protein SIX1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
D41D (p.Asp41Asp) variant details
- p.Asp41Asp
- gnomAD 14-60649067-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.404
- CADD 13.80
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available
- SIX1 Homeobox domain domainome 1.0: score 0.324
- Literature evidence available